STOCKHOLM
(AFP) - French and German scientists credited with the discovery of the viruses
behind AIDS and cervical cancer won Monday
the Nobel Medicine Prize, the first of the prestigious awards to be announced
this year.
Harald zur Hausen of Germany won the
other half of the award for going against the then-current dogma and claiming
that a virus, the human papilloma virus
(HPV),
causes cervical cancer, the second most common cancer among women.
The French pair's HIV discovery was
"one prerequisite for the current understanding of the biology of the
disease and its antiretroviral
treatment," the Nobel citation said.
Their work "led to development of
methods to diagnose infected patients and to screen blood products, which has
limited the spread of the pandemic,"
it said.
Montagnier dedicated his
award to AIDS sufferers and predicted results on a "therapeutic
vaccine" for the pandemic within four years.
"I think my first reaction is to think
of all the people sick with AIDS and all those who are still alive and fighting
against the illness," Montagnier told AFP.
He said a treatment could be possible in
the future with a "therapeutic" rather than preventive vaccine for
which results could be published in three or four years if the researcher can
secure financial backing.
AIDS -- acquired immune deficiency syndrome
-- first came to public notice in 1981, when
It has since killed at least 25 million
people, and 33 million others are living with the disease or harbouring HIV.
In May 1983, in a paper published in the
Their groundbreaking discovery was also
helped by
Both Montagnier
and Gallo are co-credited with discovering that HIV causes AIDS, although for
several years they staked rival claims that led to a legal and even diplomatic
dispute between
The Nobel jury made no mention of Gallo in
its citation.
"We gave the prize for the discovery
of the virus. The two to whom we gave the prize, Francoise Barre-Sinoussi
and Luc Montagnier,
discovered the virus," Hans Joernvall of the
Nobel committee told AFP.
Acknowledging that the American had
"done a lot of other work" in the field, Joernvall
noted that Gallo and the two French scientists now "agree that the
discovery was made in
Another member of the jury, Bjoern Vennstroem, said he hoped
the award would silence those who claim that HIV does not cause AIDS.
"We hope this will put an end to
conspiracy theories and others who defend ideas that are not founded in
research," he told Swedish Radio.
Montagnier, 76, is a professor
emeritus and director of the World Foundation for AIDS Research
and Prevention in
"I must admit that I never for a
moment dreamt I would hear such news," Barre-Sinoussi
told French radio by telephone from
Meanwhile, Zur Hausen was rewarded for his work on what is sometimes
called "the silent killer" of women because it is often undetected
until it is too late.
"His discovery has led to characterisation of the natural history of human papilloma virus (HPV) infection, and understanding of
mechanisms of HPV-induced
carcinogenesis
and the development of prophylactic vaccines against HPV acquisition," the
jury said.
It pointed out that five percent of cancers
worldwide were caused by the virus. Fifty to 80 percent of the population is
infected with the virus, though not all infections are cancerous.
"This prize means a great deal to me
because on the one hand an area has been recognised
that has increasingly moved to the forefront in cancer research, namely the
role of infectious agents," Zur Hausen, 72, said in an interview with German television.
Today, a simple smear test can detect HPV
and there are two effective vaccines against it.
Zur Hausen is a professor emeritus and former chairman and
scientific director of the German Cancer Research Centre in
In an important spinoff of
his research, Gallo isolated growth factors that allowed other researchers to
grow HIV and study it. He also patented a blood test for the virus, a patent
disputed by the French. In 1987, the battle reached the White House, when
President Reagan and French Prime Minister Jacques Chirac agreed to divide the
royalties. Gallo and Montagnier agreed to share
credit as co-discoverers of the virus.
Montagnier told the Associated Press in
Anthony Fauci, director of the National Institute of Allergy and
Infectious Diseases, said, "Clearly the awardees are
totally deserving." But he noted that Gallo suffered from the Nobel
judges' decision to honor two discoveries. That's because the award goes to
three researchers at most.
"It's too bad that
the prize couldn't be given to four people," Fauci
says. "You could make a very strong case to include Bob in that group."
The laureates will receive a gold medal, a
diploma and 10 million Swedish kronor (1.42 million dollars, 1.02 million euros) -- half for Zur Hausen and half for the French pair -- at a formal ceremony
in